FDXACB1

Across TCGA cell cohorts, FDXACB1 mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FDXACB1-associated genes across cancer lineages are TNRC6B, TMEM33, and RGPD3. Each is linked with FDXACB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FDXACB1-to-partner and partner-to-FDXACB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TNRC6B grouped by FDXACB1-low versus FDXACB1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FDXACB1→partner) and Y-score (partner→FDXACB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TNRC6B →	+1.082	+3.064	<.001	.009	3	1
LARGE_INTESTINE	TMEM33 →	+0.689	+3.064	<.001	.009	3	1
LARGE_INTESTINE	RGPD3 →	+0.186	+3.392	<.001	.003	3	1
LARGE_INTESTINE	ABCA6 →	+0.242	+3.502	<.001	.007	3	1
LARGE_INTESTINE	DNASE1L3 →	+0.067	+3.977	.005	<.001	3	1
LARGE_INTESTINE	INSL5 →	+0.263	+2.889	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

TNRC6B by FDXACB1 expression — LARGE_INTESTINE

Explore this box plot interactively →