FDX2

Across TCGA patient cohorts, FDX2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,529 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FDX2-associated genes across cancer lineages are TCF19, MCM2, and TTK. Each is linked with FDX2 in more than 3 cancer types. Because this analysis shows association rather than direction, both FDX2-to-partner and partner-to-FDX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FDX2 versus TCF19 in BRCA, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FDX2→partner) and Y-score (partner→FDX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TCF19 →	-0.812	-0.289	<.001	.006	3	4
COAD	MCM2 →	-0.837	-0.364	<.001	<.001	3	4
BRCA	TTK →	-1.066	-0.294	<.001	<.001	3	4
BRCA	NUTF2 →	-0.426	-0.291	.001	.002	3	3
BRCA	CEP55 →	-1.022	-0.308	<.001	<.001	3	3
BRCA	SPTBN4 →	+0.953	+0.356	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,529 associations by consensus.

FDX2 vs TCF19 — BRCA

Explore this scatter interactively →