FDX2

Across TCGA cell cohorts, FDX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,332 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FDX2-associated GO terms across cancer lineages are P450-containing electron transport chain, Regulation of glycolytic process through fructose-6-phosphate, and Negative regulation of glycolytic process through fructose-6-phosphate. Each is linked with FDX2 in more than 13 cancer types. Because this analysis shows association rather than direction, both FDX2-to-partner and partner-to-FDX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, P450-containing electron transport chain grouped by FDX2-low versus FDX2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FDX2→partner) and Y-score (partner→FDX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	P450-containing electron transport chain →	+0.139	+0.889	.001	<.001	2	14
LIVER	Regulation of glycolytic process through fructose-6-phosphate →	+0.137	+0.696	.007	.001	2	12
LIVER	Negative regulation of glycolytic process through fructose-6-phosphate →	+0.137	+0.696	.007	.001	2	12
UPPER_AERODIGESTIVE_TRACT	Inner mitochondrial membrane organization →	+0.076	+0.772	<.001	<.001	3	9
BLOOD_Lymphoma	7-methylguanosine cap hypermethylation →	+0.074	+0.766	<.001	<.001	3	9
BLOOD_Myeloma	Protein insertion into membrane →	+0.070	+1.141	.002	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,332 associations by consensus.

P450-containing electron transport chain by FDX2 expression — OESOPHAGUS

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