FDX1

Across TCGA patient cohorts, FDX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,168 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible FDX1-associated GO terms across cancer lineages are snRNA catabolic process, Branched-chain amino acid catabolic process, and Mitochondrial RNA catabolic process. Each is linked with FDX1 in more than 23 cancer types. Because this analysis shows association rather than direction, both FDX1-to-partner and partner-to-FDX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, snRNA catabolic process grouped by FDX1-low versus FDX1-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FDX1→partner) and Y-score (partner→FDX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	snRNA catabolic process →	+0.076	+0.377	.003	.001	1	24
KICH	Branched-chain amino acid catabolic process →	+0.064	+1.312	<.001	<.001	3	21
UVM	Mitochondrial RNA catabolic process →	+0.067	+0.872	<.001	<.001	3	21
UVM	Regulation of mitochondrial mRNA stability →	+0.069	+0.986	<.001	<.001	3	20
TGCT	Valine metabolic process →	+0.055	+0.529	<.001	<.001	3	20
THYM	Succinate metabolic process →	+0.085	+0.522	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,168 associations by consensus.

snRNA catabolic process by FDX1 expression — SCLC

Explore this box plot interactively →