FDX1

Across TCGA patient cohorts, FDX1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,876 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FDX1-associated genes across cancer lineages are RBFOX2, BACH2, and CHSY3. Each is linked with FDX1 in more than 3 cancer types. Because this analysis shows association rather than direction, both FDX1-to-partner and partner-to-FDX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FDX1 versus RBFOX2 in OV, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FDX1→partner) and Y-score (partner→FDX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RBFOX2 →	-0.558	-0.405	.002	.001	3	4
GBM	BACH2 →	-0.658	-0.375	.004	.002	3	4
OV	CHSY3 →	-0.895	-0.601	<.001	<.001	3	4
HNSC	SDHD →	+0.770	+0.281	<.001	<.001	3	4
HNSC	DLAT →	+0.532	+0.366	.003	<.001	3	4
HNSC	SIAE →	+0.568	+0.416	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,876 associations by consensus.

FDX1 vs RBFOX2 — OV

Explore this scatter interactively →