FDPSP2

Across TCGA pan-cancer cohorts, FDPSP2 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated FDPSP2 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher FDPSP2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FDPSP2 expression acts as an unfavorable survival marker, although some lineages such as BLCA and BRCA show a favorable association.

UVM, LIHC, and OV are the cancer types where FDPSP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.422	0.889	<.001	96	view →
LIHC	DFS	Quartile	III,IV	0.126	0.337	.002	81	view →
OV	DFS	Quartile	III,IV	0.437	0.567	.002	66	view →
BLCA	OS	Median	III,IV	0.466	0.280	.001	43	view →
BRCA	DFS	Median	III,IV	0.854	0.730	.004	43	view →
THCA	OS	Tertile	II,III,IV	0.929	0.989	.004	21	view →
SKCM	DFS	Tertile	III,IV	0.646	0.408	.004	15	view →
KIRC	OS	Median	All	0.563	0.712	.010	14	view →
MESO	DFS	Quartile	IV	0.100	0.389	.002	12	view →
ESCA	OS	Tertile	IV	0.373	0.916	.024	11	view →
COAD	OS	Median	III,IV	0.748	0.337	.003	8	view →
GBM	OS	Tertile	All	0.332	0.458	.015	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

FDPSP2–UVM (OS)

Open the UVM breakdown →