FDFT1

Across TCGA patient cohorts, FDFT1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,878 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FDFT1-associated genes across cancer lineages are HMGCR, HMGCS1, and ACAT2. Each is linked with FDFT1 in more than 6 cancer types. Because this analysis shows association rather than direction, both FDFT1-to-partner and partner-to-FDFT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FDFT1 versus HMGCR in HNSC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FDFT1→partner) and Y-score (partner→FDFT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HMGCR →	+0.875	+0.812	<.001	<.001	3	7
HNSC	HMGCS1 →	+0.780	+0.711	<.001	<.001	3	7
HNSC	ACAT2 →	+0.908	+0.648	.001	<.001	3	7
LSCC	FDPS →	+0.721	+0.868	<.001	<.001	3	7
HNSC	INSIG1 →	+0.835	+0.645	<.001	<.001	3	7
COAD	MSMO1 →	+0.850	+0.583	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,878 associations by consensus.

FDFT1 vs HMGCR — HNSC

Explore this scatter interactively →