FDFT1

Across TCGA patient cohorts, FDFT1 mutation is significantly associated with the RNA expression of many other genes, with 184 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FDFT1-associated genes across cancer lineages are RNA5SP412, RNU6-340P, and MTCO2P4. Each is linked with FDFT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FDFT1-to-partner and partner-to-FDFT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by FDFT1-low versus FDFT1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FDFT1→partner) and Y-score (partner→FDFT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.988	+2.704	<.001	.004	3	3
CESC	RNU6-340P →	+0.364	+5.342	<.001	.002	3	2
SKCM	MTCO2P4 →	+0.229	+5.224	<.001	.007	3	2
CESC	RNA5SP303 →	+0.241	+4.969	<.001	.004	3	2
UCEC	RNA5SP419 →	+1.394	+3.340	<.001	<.001	3	2
UCEC	RNA5SP418 →	+1.384	+2.600	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 184 associations by consensus.

RNA5SP412 by FDFT1 expression — UCEC

Explore this box plot interactively →