FCSK

Across TCGA patient cohorts, FCSK protein abundance is significantly associated with the RNA expression of many other genes, with 11,980 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FCSK-associated genes across cancer lineages are NCAPG, CCNB1, and KIF11. Each is linked with FCSK in more than 6 cancer types. Because this analysis shows association rather than direction, both FCSK-to-partner and partner-to-FCSK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FCSK versus NCAPG in GBM, with a Pearson correlation of -0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCSK→partner) and Y-score (partner→FCSK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NCAPG →	-1.098	-0.212	<.001	<.001	3	7
LUAD	CCNB1 →	-1.218	-0.382	<.001	<.001	3	7
GBM	KIF11 →	-1.026	-0.284	<.001	<.001	3	7
GBM	CENPE →	-0.944	-0.203	<.001	<.001	3	7
OV	PTTG1 →	-0.948	-0.407	<.001	<.001	3	7
GBM	NDC80 →	-1.028	-0.227	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,980 associations by consensus.

FCSK vs NCAPG — GBM

Explore this scatter interactively →