FCSK

Across TCGA cell cohorts, FCSK RNA expression is significantly associated with the go_rna of many other GO terms, with 4,673 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FCSK-associated GO terms across cancer lineages are Taurine biosynthetic process, Alkanesulfonate biosynthetic process, and Late viral transcription. Each is linked with FCSK in more than 16 cancer types. Because this analysis shows association rather than direction, both FCSK-to-partner and partner-to-FCSK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Taurine biosynthetic process grouped by FCSK-low versus FCSK-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FCSK→partner) and Y-score (partner→FCSK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Taurine biosynthetic process →	+1.143	+0.869	.001	.003	3	16
UPPER_AERODIGESTIVE_TRACT	Alkanesulfonate biosynthetic process →	+1.143	+0.869	.001	.003	3	16
BONE	Late viral transcription →	+0.136	+0.905	<.001	<.001	3	16
URINARY_TRACT	Cilium or flagellum-dependent cell motility →	-0.119	-1.210	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Viral transcription →	+0.117	+0.831	.008	.002	1	17
STOMACH	GDP-L-fucose biosynthetic process →	+0.112	+0.944	.002	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,673 associations by consensus.

Taurine biosynthetic process by FCSK expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →