FCRLB

Across TCGA cell cohorts, FCRLB mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible FCRLB-associated genes across cancer lineages are CBLN4, MAGEB4, and GNG8. Each is linked with FCRLB in more than 1 cancer types. Because this analysis shows association rather than direction, both FCRLB-to-partner and partner-to-FCRLB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CBLN4 grouped by FCRLB-low versus FCRLB-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCRLB→partner) and Y-score (partner→FCRLB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CBLN4 →	+0.006	+5.539	<.001	.003	3	1
LUNG_NSCLC_LUAD	MAGEB4 →	+0.006	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	GNG8 →	+0.271	+4.887	.001	.009	3	1
LUNG_NSCLC_LUAD	OR2L8 →	+0.020	+6.266	<.001	<.001	3	1
CNS	GUCA2B →	+0.043	+4.981	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CBLN4 by FCRLB expression — BLOOD_Leukemia

Explore this box plot interactively →