FCRL6

Across TCGA cell cohorts, FCRL6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,383 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FCRL6-associated GO terms across cancer lineages are Endocytic recycling, Negative regulation of myoblast fusion, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with FCRL6 in more than 6 cancer types. Because this analysis shows association rather than direction, both FCRL6-to-partner and partner-to-FCRL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endocytic recycling grouped by FCRL6-low versus FCRL6-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FCRL6→partner) and Y-score (partner→FCRL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Endocytic recycling →	+0.067	+0.044	<.001	.002	3	7
LUNG_SCLC	Negative regulation of myoblast fusion →	+0.092	+0.234	<.001	.003	3	7
LUNG_SCLC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.091	+0.234	<.001	.003	3	7
LUNG_SCLC	Regulation of translational initiation →	+0.052	+0.219	.001	.007	3	6
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.083	+0.269	<.001	.005	3	6
SOFT_TISSUE	Cellular response to type I interferon →	+0.065	+0.070	.002	.009	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,383 associations by consensus.

Endocytic recycling by FCRL6 expression — SOFT_TISSUE

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