FCRL5

Across TCGA patient cohorts, FCRL5 protein abundance is significantly associated with the RNA expression of many other genes, with 8,330 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FCRL5-associated genes across cancer lineages are SLC25A14, P2RX1, and POU2AF1. Each is linked with FCRL5 in more than 3 cancer types. Because this analysis shows association rather than direction, both FCRL5-to-partner and partner-to-FCRL5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FCRL5 versus SLC25A14 in HNSC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCRL5→partner) and Y-score (partner→FCRL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SLC25A14 →	-0.459	-0.438	<.001	.005	3	4
HNSC	P2RX1 →	+0.944	+0.455	.004	.009	3	4
HNSC	POU2AF1 →	+1.493	+0.656	.002	.001	3	4
HNSC	LAX1 →	+1.701	+0.617	.006	.001	3	4
HNSC	IRF4 →	+1.413	+0.688	.005	<.001	3	4
LUAD	CD19 →	+1.044	+0.530	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,330 associations by consensus.

FCRL5 vs SLC25A14 — HNSC

Explore this scatter interactively →