FCRL5

Across TCGA cell cohorts, FCRL5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,254 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FCRL5-associated GO terms across cancer lineages are Response to transition metal nanoparticle, Endosomal transport, and Regulation of iron ion transmembrane transport. Each is linked with FCRL5 in more than 7 cancer types. Because this analysis shows association rather than direction, both FCRL5-to-partner and partner-to-FCRL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to transition metal nanoparticle grouped by FCRL5-low versus FCRL5-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FCRL5→partner) and Y-score (partner→FCRL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Response to transition metal nanoparticle →	-0.220	-0.063	<.001	.002	3	8
SKIN	Endosomal transport →	+0.047	+0.025	.001	.002	3	6
SKIN	Regulation of iron ion transmembrane transport →	-0.283	-0.028	<.001	<.001	3	6
PANCREAS	Positive regulation of autophagy of mitochondrion →	+0.061	+0.021	.003	.004	3	6
BONE	Positive regulation of protein localization to nucleus →	+0.059	+0.023	.009	.006	2	7
LARGE_INTESTINE	Regulation of ubiquitin-dependent protein catabolic process →	+0.051	+0.043	<.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,254 associations by consensus.

Response to transition metal nanoparticle by FCRL5 expression — CNS

Explore this box plot interactively →