FCRL3

Across TCGA cell cohorts, FCRL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,428 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FCRL3-associated GO terms across cancer lineages are Positive regulation of mRNA catabolic process, Microtubule nucleation, and Negative regulation of autophagosome maturation. Each is linked with FCRL3 in more than 6 cancer types. Because this analysis shows association rather than direction, both FCRL3-to-partner and partner-to-FCRL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mRNA catabolic process grouped by FCRL3-low versus FCRL3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FCRL3→partner) and Y-score (partner→FCRL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of mRNA catabolic process →	+0.047	+0.033	.001	.002	3	7
SOFT_TISSUE	Microtubule nucleation →	+0.071	+0.018	.001	.005	3	6
BLOOD_Lymphoma	Negative regulation of autophagosome maturation →	+0.100	+1.746	<.001	.001	3	5
OESOPHAGUS	Regulation of TOR signaling →	+0.052	+0.025	<.001	.009	3	5
SOFT_TISSUE	Positive regulation of telomere capping →	+0.077	+0.019	<.001	.003	3	5
LARGE_INTESTINE	DNA-templated transcription initiation →	+0.053	+0.053	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,428 associations by consensus.

Positive regulation of mRNA catabolic process by FCRL3 expression — SOFT_TISSUE

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