FCRL2

Across TCGA cell cohorts, FCRL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,372 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FCRL2-associated GO terms across cancer lineages are Negative regulation of autophagosome maturation, Granulocyte colony-stimulating factor signaling pathway, and Positive regulation of D-glucose transmembrane transport. Each is linked with FCRL2 in more than 4 cancer types. Because this analysis shows association rather than direction, both FCRL2-to-partner and partner-to-FCRL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of autophagosome maturation grouped by FCRL2-low versus FCRL2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FCRL2→partner) and Y-score (partner→FCRL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of autophagosome maturation →	+0.091	+1.908	<.001	<.001	2	5
UPPER_AERODIGESTIVE_TRACT	Granulocyte colony-stimulating factor signaling pathway →	-0.151	-0.022	.005	.006	3	4
OVARY	Positive regulation of D-glucose transmembrane transport →	+0.055	+0.012	<.001	.002	3	4
UPPER_AERODIGESTIVE_TRACT	MHC class II protein complex assembly →	-0.252	-0.032	.009	.008	3	4
UPPER_AERODIGESTIVE_TRACT	Peptide antigen assembly with MHC class II protein complex →	-0.252	-0.032	.009	.008	3	4
SOFT_TISSUE	Mitochondrial translational elongation →	-0.096	-0.022	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,372 associations by consensus.

Negative regulation of autophagosome maturation by FCRL2 expression — BLOOD_Lymphoma

Explore this box plot interactively →