FCRL2

Across TCGA cell cohorts, FCRL2 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible FCRL2-associated genes across cancer lineages are CCDC172, TBC1D3H, and VN1R3. Each is linked with FCRL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FCRL2-to-partner and partner-to-FCRL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC172 grouped by FCRL2-low versus FCRL2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCRL2→partner) and Y-score (partner→FCRL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CCDC172 →	+0.039	+4.369	<.001	.008	3	2
LUNG_NSCLC_LUAD	TBC1D3H →	+0.878	+3.523	<.001	<.001	3	2
SOFT_TISSUE	VN1R3 →	+0.025	+4.977	<.001	.002	3	1
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUAD	DSPP →	+0.023	+3.906	.002	.002	3	1
LUNG_NSCLC_LUAD	DMP1 →	+0.069	+3.438	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

CCDC172 by FCRL2 expression — SOFT_TISSUE

Explore this box plot interactively →