FCRL1

Across TCGA cell cohorts, FCRL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,570 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FCRL1-associated GO terms across cancer lineages are Cellular detoxification, Positive regulation of protein targeting to membrane, and Detoxification. Each is linked with FCRL1 in more than 3 cancer types. Because this analysis shows association rather than direction, both FCRL1-to-partner and partner-to-FCRL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular detoxification grouped by FCRL1-low versus FCRL1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FCRL1→partner) and Y-score (partner→FCRL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Cellular detoxification →	-0.068	-1.831	<.001	<.001	3	4
BLOOD_Myeloma	Positive regulation of protein targeting to membrane →	-0.111	-0.728	<.001	.005	3	4
BLOOD_Lymphoma	Detoxification →	-0.087	-2.009	<.001	<.001	3	4
LARGE_INTESTINE	Protein deubiquitination →	+0.040	+0.073	<.001	.004	3	4
BLOOD_Lymphoma	Positive regulation of autophagy of mitochondrion →	+0.050	+1.679	.001	.008	3	4
BLOOD_Lymphoma	Macrophage migration →	-0.230	-1.867	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,570 associations by consensus.

Cellular detoxification by FCRL1 expression — BLOOD_Lymphoma

Explore this box plot interactively →