FCRL1

Across TCGA cell cohorts, FCRL1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible FCRL1-associated genes across cancer lineages are TAAR8, SPATA48, and OR1D4. Each is linked with FCRL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FCRL1-to-partner and partner-to-FCRL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAAR8 grouped by FCRL1-low versus FCRL1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCRL1→partner) and Y-score (partner→FCRL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TAAR8 →	+0.017	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	SPATA48 →	+0.009	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR1D4 →	+0.046	+4.662	<.001	.005	3	1
SKIN	GGT2 →	+0.116	+3.242	<.001	.003	3	1
SKIN	KRTAP13-1 →	+0.018	+3.700	<.001	.009	3	1
OVARY	RBMY1A1 →	+0.143	+5.807	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

TAAR8 by FCRL1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →