FCN2

Across TCGA cell cohorts, FCN2 mutation is significantly associated with the RNA expression of many other genes, with 238 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FCN2-associated genes across cancer lineages are CDRT15L2, GTSF1L, and OR1G1. Each is linked with FCN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FCN2-to-partner and partner-to-FCN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDRT15L2 grouped by FCN2-low versus FCN2-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCN2→partner) and Y-score (partner→FCN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CDRT15L2 →	+0.411	+4.269	<.001	.005	3	1
LUNG_NSCLC_LUAD	GTSF1L →	+0.045	+4.544	<.001	.003	3	1
BLOOD_Leukemia	OR1G1 →	+0.101	+4.705	<.001	.003	3	1
BLOOD_Leukemia	KRTAP10-12 →	+0.190	+4.539	<.001	.007	3	1
BLOOD_Leukemia	C16orf90 →	+0.033	+4.152	.001	.009	3	1
BLOOD_Leukemia	OR1D4 →	+0.046	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 238 associations by consensus.

CDRT15L2 by FCN2 expression — LUNG_SCLC

Explore this box plot interactively →