FCN1

Across TCGA cell cohorts, FCN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,094 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FCN1-associated GO terms across cancer lineages are Calcium import into the mitochondrion, Negative regulation of immunoglobulin production, and Exploration behavior. Each is linked with FCN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FCN1-to-partner and partner-to-FCN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Calcium import into the mitochondrion grouped by FCN1-low versus FCN1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FCN1→partner) and Y-score (partner→FCN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Calcium import into the mitochondrion →	-0.070	-0.107	.009	.009	3	3
BLOOD_Leukemia	Negative regulation of immunoglobulin production →	-0.114	-1.014	.001	<.001	3	3
BLOOD_Leukemia	Exploration behavior →	-0.063	-0.816	.004	.004	3	3
LUNG_SCLC	Carbon dioxide transport →	+2.209	+0.189	<.001	<.001	3	2
LUNG_SCLC	Protein nitrosylation →	-0.202	-0.113	<.001	<.001	3	2
LUNG_SCLC	Peptidyl-cysteine S-nitrosylation →	-0.202	-0.113	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,094 associations by consensus.

Calcium import into the mitochondrion by FCN1 expression — LUNG_SCLC

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