FCHSD2

Across TCGA cell cohorts, FCHSD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,362 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FCHSD2-associated GO terms across cancer lineages are Positive regulation of Arp2/3 complex-mediated actin nucleation, Regulation of hippo signaling, and Cell division. Each is linked with FCHSD2 in more than 11 cancer types. Because this analysis shows association rather than direction, both FCHSD2-to-partner and partner-to-FCHSD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of Arp2/3 complex-mediated actin nucleation grouped by FCHSD2-low versus FCHSD2-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FCHSD2→partner) and Y-score (partner→FCHSD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Positive regulation of Arp2/3 complex-mediated actin nucleation →	+0.150	+1.116	<.001	<.001	3	12
OESOPHAGUS	Regulation of hippo signaling →	+0.104	+1.335	.002	<.001	3	12
SOFT_TISSUE	Cell division →	+0.060	+0.547	.002	.006	3	11
OESOPHAGUS	Centriole-centriole cohesion →	+0.061	+0.997	.008	.004	3	11
CNS	Hormone metabolic process →	-0.073	-0.569	<.001	<.001	3	10
BLOOD_Leukemia	Nuclear transport →	+0.048	+0.806	.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,362 associations by consensus.

Positive regulation of Arp2/3 complex-mediated actin nucleation by FCHSD2 expression — BLOOD_Leukemia

Explore this box plot interactively →