FCHSD2

Across TCGA cell cohorts, FCHSD2 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FCHSD2-associated genes across cancer lineages are OR5C1, TEX36, and CCDC177. Each is linked with FCHSD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FCHSD2-to-partner and partner-to-FCHSD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5C1 grouped by FCHSD2-low versus FCHSD2-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCHSD2→partner) and Y-score (partner→FCHSD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	OR5C1 →	+0.028	+4.044	<.001	.001	3	1
URINARY_TRACT	TEX36 →	+0.273	+3.584	.007	.005	3	1
URINARY_TRACT	CCDC177 →	+0.021	+3.906	<.001	.009	3	1
URINARY_TRACT	ZNF728 →	+0.286	+4.321	.004	.001	3	1
STOMACH	OR11A1 →	+0.016	+5.285	<.001	.003	3	1
STOMACH	OR5V1 →	+0.056	+5.285	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

OR5C1 by FCHSD2 expression — URINARY_TRACT

Explore this box plot interactively →