Across TCGA patient cohorts, FCHSD1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,572 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FCHSD1-associated genes across cancer lineages are SUV39H2, CD33, and CAV1. Each is linked with FCHSD1 in more than 5 cancer types. Because this analysis shows association rather than direction, both FCHSD1-to-partner and partner-to-FCHSD1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCHSD1→partner) and Y-score (partner→FCHSD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SUV39H2 →	-0.786	-0.310	<.001	<.001	3	6
GBM	CD33 →	+0.636	+0.375	<.001	<.001	3	5
BRCA	CAV1 →	+1.092	+0.297	.001	.005	3	5
BRCA	STARD8 →	+0.678	+0.369	<.001	<.001	3	5
UCEC	GMFG →	+1.016	+0.285	.004	.006	3	5
UCEC	CLEC10A →	+1.088	+0.371	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,572 associations by consensus.

Exploration

FCHSD1 survival (RNA) · tumor vs normal (RNA) · all FCHSD1 data types