Across TCGA patient cohorts, FCHSD1 mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FCHSD1-associated genes across cancer lineages are eEF2, PEA-15_pS116, and ATM. Each is linked with FCHSD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FCHSD1-to-partner and partner-to-FCHSD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCHSD1→partner) and Y-score (partner→FCHSD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.436	+1.847	<.001	.008	3	3
UCEC	PEA-15_pS116 →	+0.307	+1.502	.017	.030	3	3
UCEC	ATM →	-0.552	-2.687	<.001	.005	3	3
UCEC	eIF4E →	+0.195	+3.472	.011	.002	3	2
UCEC	MSH2 →	-0.339	-3.558	<.001	.002	3	2
UCEC	PDCD4 →	-0.394	-1.502	.022	.030	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

Exploration

FCHSD1 survival (RNA) · tumor vs normal (RNA) · all FCHSD1 data types