Across TCGA cell cohorts, FCHSD1 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FCHSD1-associated genes across cancer lineages are DEFA4, COX8C, and CHRNA4. Each is linked with FCHSD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FCHSD1-to-partner and partner-to-FCHSD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCHSD1→partner) and Y-score (partner→FCHSD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DEFA4 →	+0.032	+4.437	<.001	.004	3	1
LARGE_INTESTINE	COX8C →	+0.119	+3.920	<.001	.005	3	1
BLOOD_Leukemia	CHRNA4 →	+0.018	+3.234	.001	.008	3	1
BLOOD_Leukemia	FAM71A →	+0.036	+3.884	.006	.003	3	1
BLOOD_Leukemia	CRYGC →	+0.017	+3.969	.002	.009	3	1
BLOOD_Leukemia	CALHM4 →	+0.019	+3.684	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

FCHSD1 survival (RNA) · tumor vs normal (RNA) · all FCHSD1 data types