FCHO2

Across TCGA cell cohorts, FCHO2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,884 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FCHO2-associated GO terms across cancer lineages are Protein localization to vacuole, Establishment of protein localization to vacuole, and Target-directed miRNA degradation. Each is linked with FCHO2 in more than 11 cancer types. Because this analysis shows association rather than direction, both FCHO2-to-partner and partner-to-FCHO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to vacuole grouped by FCHO2-low versus FCHO2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FCHO2→partner) and Y-score (partner→FCHO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein localization to vacuole →	+0.084	+0.933	.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to vacuole →	+0.078	+1.010	.002	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Target-directed miRNA degradation →	+0.107	+0.911	.001	<.001	3	11
LUNG_SCLC	Regulation of macrophage fusion →	+0.231	+0.661	.001	<.001	3	11
LUNG_SCLC	Positive regulation of macrophage fusion →	+0.231	+0.661	.001	<.001	3	11
BONE	Protein localization to membrane →	+0.084	+0.984	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,884 associations by consensus.

Protein localization to vacuole by FCHO2 expression — BONE

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