FCHO2

Across TCGA cell cohorts, FCHO2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FCHO2-associated genes across cancer lineages are CLDN17 and L3MBTL4. Each is linked with FCHO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FCHO2-to-partner and partner-to-FCHO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLDN17 grouped by FCHO2-low versus FCHO2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCHO2→partner) and Y-score (partner→FCHO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CLDN17 →	+0.029	+5.228	<.001	.005	3	1
LARGE_INTESTINE	L3MBTL4 →	+0.810	+3.285	<.001	.007	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CLDN17 by FCHO2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →