FCHO1

Across TCGA cell cohorts, FCHO1 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FCHO1-associated genes across cancer lineages are KRTAP1-1, SPATA31A6, and GOLGA6L1. Each is linked with FCHO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FCHO1-to-partner and partner-to-FCHO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP1-1 grouped by FCHO1-low versus FCHO1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCHO1→partner) and Y-score (partner→FCHO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	KRTAP1-1 →	+0.082	+5.209	<.001	.005	3	2
URINARY_TRACT	SPATA31A6 →	+0.006	+5.087	<.001	.004	3	1
URINARY_TRACT	GOLGA6L1 →	+0.020	+5.087	<.001	.004	3	1
LUNG_SCLC	OR14A16 →	+0.091	+4.070	<.001	.003	3	1
LUNG_SCLC	OR10G2 →	+0.129	+3.523	.001	.008	3	1
OVARY	TAFA1 →	+0.064	+4.078	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

KRTAP1-1 by FCHO1 expression — BLOOD_Lymphoma

Explore this box plot interactively →