FCGRT

Across TCGA pan-cancer cohorts, FCGRT mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated FCGRT data layer compared with 30 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FCGRT mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated FCGRT expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

UCEC, LSCC, and CCRCC are the cancer types where FCGRT mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	0.467	0.946	.002	46	view →
LSCC	DFS	Quartile	II,III,IV	0.562	1.000	.005	17	view →
CCRCC	DFS	Quartile	III,IV	0.821	0.434	.019	11	view →
LUAD	OS	Median	All	0.850	0.588	.014	7	view →
HNSC	DFS	Median	II,III,IV	0.907	0.984	.035	4	view →
PDAC	OS	Median	IV	0.836	0.491	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

FCGRT–UCEC (DFS)

Open the UCEC breakdown →