FCGRT

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FCGRT protein abundance is significantly associated with the RNA expression of many other genes, with 17,354 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FCGRT-associated genes across cancer lineages are OLFML3, ABI3BP, and STAB1. Each is linked with FCGRT in more than 6 cancer types. Because this analysis shows association rather than direction, both FCGRT-to-partner and partner-to-FCGRT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FCGRT versus OLFML3 in OV, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCGRT→partner) and Y-score (partner→FCGRT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVOLFML3 →+0.939+0.330<.001<.00137
OVABI3BP →+1.249+0.396.001<.00137
GBMSTAB1 →+1.396+0.579<.001<.00136
GBMCD33 →+0.884+0.546<.001<.00136
OVCXCL12 →+1.769+0.398<.001<.00136
GBMMS4A6A →+1.246+0.558<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,354 associations by consensus.

FCGRT vs OLFML3 — OV

Per-sample scatter of FCGRT vs OLFML3 in OV (Pearson r = 0.54).

Explore this scatter interactively →

Exploration