Across TCGA pan-cancer cohorts, FCGR3A Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated FCGR3A data layer compared with 21 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FCGR3A Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated FCGR3A expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC and COAD are the cancer types where FCGR3A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	1.000	0.441	.025	20	view →
COAD	OS	Median	All	0.641	0.874	.021	1	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: FCGR3A tumor-vs-normal RNA expression · all FCGR3A data types