Across TCGA patient cohorts, FCGR3A protein abundance is significantly associated with the RNA expression of many other genes, with 16,107 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FCGR3A-associated genes across cancer lineages are NLRC5, IL21R, and LILRB4. Each is linked with FCGR3A in more than 6 cancer types. Because this analysis shows association rather than direction, both FCGR3A-to-partner and partner-to-FCGR3A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCGR3A→partner) and Y-score (partner→FCGR3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	NLRC5 →	+1.192	+0.911	<.001	.003	3	7
GBM	IL21R →	+1.359	+0.833	<.001	<.001	3	7
GBM	LILRB4 →	+1.137	+0.789	<.001	<.001	3	7
GBM	FGD2 →	+0.873	+0.732	<.001	<.001	3	7
UCEC	LINC02328 →	+0.559	+0.603	<.001	<.001	3	6
GBM	CYTH4 →	+1.186	+0.871	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,107 associations by consensus.

Exploration

FCGR3A survival (RNA) · tumor vs normal (RNA) · all FCGR3A data types