Across TCGA cell cohorts, FCGR3A RNA expression is significantly associated with the go_rna of many other GO terms, with 313 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FCGR3A-associated GO terms across cancer lineages are Oxygen transport, Spliceosomal conformational changes to generate catalytic conformation, and Proteasomal ubiquitin-independent protein catabolic process. Each is linked with FCGR3A in more than 2 cancer types. Because this analysis shows association rather than direction, both FCGR3A-to-partner and partner-to-FCGR3A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FCGR3A→partner) and Y-score (partner→FCGR3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Oxygen transport →	+1.361	+0.107	<.001	<.001	3	3
STOMACH	Spliceosomal conformational changes to generate catalytic conformation →	+0.110	+0.052	<.001	.003	3	3
PANCREAS	Proteasomal ubiquitin-independent protein catabolic process →	+0.067	+0.009	.008	.008	3	3
BLOOD_Leukemia	Granzyme-mediated programmed cell death signaling pathway →	+0.100	+0.081	<.001	.005	3	2
BLOOD_Leukemia	Protein polyglutamylation →	-0.047	-0.066	.003	.008	3	2
BLOOD_Leukemia	Positive regulation of regulated secretory pathway →	+0.062	+0.055	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 313 associations by consensus.

Exploration

FCGR3A survival (RNA) · tumor vs normal (RNA) · all FCGR3A data types