Across TCGA cell cohorts, FCGR3A mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FCGR3A-associated genes across cancer lineages are GPR50, MYOD1, and SLC22A7. Each is linked with FCGR3A in more than 1 cancer types. Because this analysis shows association rather than direction, both FCGR3A-to-partner and partner-to-FCGR3A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCGR3A→partner) and Y-score (partner→FCGR3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GPR50 →	+0.073	+4.321	<.001	.002	3	1
BLOOD_Leukemia	MYOD1 →	+0.021	+4.507	<.001	.001	3	1
BLOOD_Leukemia	SLC22A7 →	+0.032	+3.944	.009	.006	3	1
BLOOD_Leukemia	XAGE3 →	+0.092	+4.450	<.001	.001	3	1
BLOOD_Leukemia	LRRC3C →	+0.093	+3.796	<.001	.008	3	1
BLOOD_Leukemia	AGBL1 →	+0.309	+3.944	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

FCGR3A survival (RNA) · tumor vs normal (RNA) · all FCGR3A data types