FCGR2B

Across TCGA patient cohorts, FCGR2B RNA expression is significantly associated with the protein abundance of many other proteins, with 26,009 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FCGR2B-associated proteins across cancer lineages are PTPN7, ARHGAP45, and ARHGAP9. Each is linked with FCGR2B in more than 9 cancer types. Because this analysis shows association rather than direction, both FCGR2B-to-partner and partner-to-FCGR2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FCGR2B versus PTPN7 in UCEC, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FCGR2B→partner) and Y-score (partner→FCGR2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PTPN7 →	+0.576	+0.895	<.001	<.001	3	10
GBM	ARHGAP45 →	+0.618	+1.390	<.001	<.001	3	10
GBM	ARHGAP9 →	+0.586	+1.338	<.001	<.001	3	10
UCEC	PLEK →	+0.496	+0.742	<.001	<.001	3	10
COAD	PLEKHO2 →	+0.415	+1.029	<.001	<.001	3	10
GBM	CD14 →	+0.813	+1.335	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 26,009 associations by consensus.

FCGR2B vs PTPN7 — UCEC

Explore this scatter interactively →