FCGR2B

Across TCGA patient cohorts, FCGR2B protein abundance is significantly associated with the RNA expression of many other genes, with 22,974 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FCGR2B-associated genes across cancer lineages are PIK3R5, LAIR1, and ARHGAP9. Each is linked with FCGR2B in more than 7 cancer types. Because this analysis shows association rather than direction, both FCGR2B-to-partner and partner-to-FCGR2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FCGR2B versus PIK3R5 in GBM, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCGR2B→partner) and Y-score (partner→FCGR2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PIK3R5 →	+0.965	+0.761	<.001	<.001	3	8
GBM	LAIR1 →	+1.274	+1.100	<.001	<.001	3	8
HNSC	ARHGAP9 →	+0.881	+0.402	<.001	<.001	3	7
GBM	LAPTM5 →	+1.077	+0.994	<.001	<.001	3	7
GBM	THEMIS2 →	+1.104	+0.992	<.001	<.001	3	7
OV	NCF1B →	+0.819	+0.503	.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,974 associations by consensus.

FCGR2B vs PIK3R5 — GBM

Explore this scatter interactively →