FCGR2B

Across TCGA patient cohorts, FCGR2B mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FCGR2B-associated genes across cancer lineages are Chondrocytes, Fibroblasts, and Endothelial cells. Each is linked with FCGR2B in more than 1 cancer types. Because this analysis shows association rather than direction, both FCGR2B-to-partner and partner-to-FCGR2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chondrocytes grouped by FCGR2B-low versus FCGR2B-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCGR2B→partner) and Y-score (partner→FCGR2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Chondrocytes →	+0.034	+4.694	<.001	.014	3	1
LUSC	Fibroblasts →	+0.057	+4.881	<.001	.011	3	1
UCEC	Endothelial cells →	-0.036	-2.978	.040	.036	3	1
UCEC	lymphatic Endothelial cells →	-0.024	-2.968	.033	.036	3	1
UCEC	MEP →	+0.035	+2.595	.007	.006	3	1
UCEC	Th2 cells →	+0.182	+3.008	.030	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Chondrocytes by FCGR2B expression — LUSC

Explore this box plot interactively →