FCGR2B

Across TCGA cell cohorts, FCGR2B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,518 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FCGR2B-associated GO terms across cancer lineages are Regulation of immune complex clearance by monocytes and macrophages, Antibody-dependent cellular cytotoxicity, and Type IIa hypersensitivity. Each is linked with FCGR2B in more than 12 cancer types. Because this analysis shows association rather than direction, both FCGR2B-to-partner and partner-to-FCGR2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of immune complex clearance by monocytes and macrophages grouped by FCGR2B-low versus FCGR2B-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FCGR2B→partner) and Y-score (partner→FCGR2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of immune complex clearance by monocytes and macrophages →	+1.557	+3.626	<.001	<.001	3	13
SKIN	Antibody-dependent cellular cytotoxicity →	+1.882	+0.947	<.001	<.001	3	5
SKIN	Type IIa hypersensitivity →	+1.882	+0.947	<.001	<.001	3	5
SKIN	Type II hypersensitivity →	+1.882	+0.947	<.001	<.001	3	5
BLOOD_Leukemia	Apoptotic signaling pathway →	+0.035	+2.158	<.001	<.001	3	5
LUNG_NSCLC_LUSC	Negative regulation of G1/S transition of mitotic cell cycle →	+0.059	+0.054	.004	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,518 associations by consensus.

Regulation of immune complex clearance by monocytes and macrophages by FCGR2B expression — BLOOD_Lymphoma

Explore this box plot interactively →