FCGR2B

Across TCGA cell cohorts, FCGR2B mutation is significantly associated with the mutation status of many other genes, with 1,741 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FCGR2B-associated genes across cancer lineages are ACO1, ANO3, and DPEP3. Each is linked with FCGR2B in more than 1 cancer types. Because this analysis shows association rather than direction, both FCGR2B-to-partner and partner-to-FCGR2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACO1 grouped by FCGR2B-low versus FCGR2B-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCGR2B→partner) and Y-score (partner→FCGR2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	ACO1 →	+4.297	+4.857	.009	.009	1	2
BREAST	ANO3 →	+4.297	+4.857	.009	.009	1	2
BREAST	DPEP3 →	+4.297	+4.857	.009	.009	1	2
BREAST	PNRC1 →	+5.297	+5.297	.004	.004	1	2
BREAST	SLC22A9 →	+4.297	+4.857	.009	.009	1	2
BREAST	TGFBR2 →	+5.297	+5.297	.004	.004	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,741 associations by consensus.

ACO1 by FCGR2B expression — BREAST

Explore this box plot interactively →