FCER2

Across TCGA cell cohorts, FCER2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,359 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FCER2-associated GO terms across cancer lineages are Negative regulation of autophagosome maturation, Regulation of serotonin secretion, and T cell proliferation involved in immune response. Each is linked with FCER2 in more than 5 cancer types. Because this analysis shows association rather than direction, both FCER2-to-partner and partner-to-FCER2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of autophagosome maturation grouped by FCER2-low versus FCER2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FCER2→partner) and Y-score (partner→FCER2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of autophagosome maturation →	+0.066	+1.822	<.001	<.001	3	6
BLOOD_Lymphoma	Regulation of serotonin secretion →	+1.085	+2.557	.001	.001	3	5
BLOOD_Lymphoma	T cell proliferation involved in immune response →	+1.025	+2.858	.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	Cellular response to morphine →	+0.128	+0.025	.002	.002	3	5
UPPER_AERODIGESTIVE_TRACT	Cellular response to isoquinoline alkaloid →	+0.128	+0.025	.002	.002	3	5
BLOOD_Myeloma	Regulation of type I interferon production →	+0.057	+2.808	<.001	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,359 associations by consensus.

Negative regulation of autophagosome maturation by FCER2 expression — BLOOD_Lymphoma

Explore this box plot interactively →