FCER1G

Across TCGA pan-cancer cohorts, FCER1G mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated FCER1G data layer compared with 20 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher FCER1G mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated FCER1G expression acts as an unfavorable survival marker, although some lineages such as LSCC and HNSC show a favorable association.

COAD, PDAC, and CCRCC are the cancer types where FCER1G mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.879	1.000	.010	114	view →
PDAC	DFS	Quartile	All	0.266	0.571	<.001	71	view →
CCRCC	OS	Median	All	0.773	0.903	.036	8	view →
GBM	OS	Tertile	All	0.386	0.632	.003	6	view →
LSCC	OS	Median	III,IV	1.000	0.739	.008	4	view →
LUAD	OS	Median	II,III,IV	0.863	0.999	.037	3	view →
UCEC	DFS	Median	All	0.855	0.955	.028	2	view →
HNSC	OS	Median	III,IV	1.000	0.484	.038	2	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

FCER1G–COAD (DFS)

Open the COAD breakdown →