FCER1G

Across TCGA patient cohorts, FCER1G mutation is significantly associated with the RNA expression of many other genes, with 124 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FCER1G-associated genes across cancer lineages are METTL1P1, FXNP2, and SMIM12P1. Each is linked with FCER1G in more than 1 cancer types. Because this analysis shows association rather than direction, both FCER1G-to-partner and partner-to-FCER1G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, METTL1P1 grouped by FCER1G-low versus FCER1G-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCER1G→partner) and Y-score (partner→FCER1G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	METTL1P1 →	+0.303	+4.267	<.001	<.001	3	1
UCEC	FXNP2 →	+0.344	+4.261	<.001	<.001	3	1
UCEC	SMIM12P1 →	+0.338	+3.550	.003	.001	3	1
UCEC	RN7SKP4 →	+0.316	+3.806	.007	<.001	3	1
UCEC	MIR7702 →	+0.469	+5.475	<.001	.001	3	1
UCEC	MIR6839 →	+0.477	+3.562	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 124 associations by consensus.

METTL1P1 by FCER1G expression — UCEC

Explore this box plot interactively →