FCER1A

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FCER1A mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FCER1A-associated genes across cancer lineages are FTMT, MAGEB4, and OR10W1. Each is linked with FCER1A in more than 1 cancer types. Because this analysis shows association rather than direction, both FCER1A-to-partner and partner-to-FCER1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FTMT grouped by FCER1A-low versus FCER1A-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCER1A→partner) and Y-score (partner→FCER1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCFTMT →+0.177+5.029<.001.00632
LARGE_INTESTINEMAGEB4 →+0.012+5.415.009.00431
LARGE_INTESTINEOR10W1 →+0.022+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

FTMT by FCER1A expression — LUNG_SCLC

Box plot of FTMT in FCER1A-low vs FCER1A-high samples in LUNG_SCLC.

Explore this box plot interactively →

Exploration