FBXW9

Across TCGA cell cohorts, FBXW9 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,731 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FBXW9-associated GO terms across cancer lineages are Energy coupled proton transmembrane transport, against electrochemical gradient, Electron transport coupled proton transport, and Negative regulation of protein localization to chromatin. Each is linked with FBXW9 in more than 14 cancer types. Because this analysis shows association rather than direction, both FBXW9-to-partner and partner-to-FBXW9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Energy coupled proton transmembrane transport, against electrochemical gradient grouped by FBXW9-low versus FBXW9-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXW9→partner) and Y-score (partner→FBXW9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.084	+0.745	.007	.004	3	15
BONE	Electron transport coupled proton transport →	+0.084	+0.745	.007	.004	3	15
BONE	Negative regulation of protein localization to chromatin →	+0.114	+0.571	<.001	.004	3	12
OESOPHAGUS	Cellular detoxification of methylglyoxal →	+0.131	+0.637	.004	<.001	3	11
OVARY	Regulation of glucose mediated signaling pathway →	+0.091	+0.546	.004	.002	2	12
OVARY	Positive regulation of glucose mediated signaling pathway →	+0.091	+0.546	.004	.002	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,731 associations by consensus.

Energy coupled proton transmembrane transport, against electrochemical gradient by FBXW9 expression — BONE

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