FBXW2

Across TCGA patient cohorts, FBXW2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,647 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FBXW2-associated proteins across cancer lineages are EHMT1, BRD3, and ECPAS. Each is linked with FBXW2 in more than 7 cancer types. Because this analysis shows association rather than direction, both FBXW2-to-partner and partner-to-FBXW2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXW2 versus EHMT1 in COAD, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXW2→partner) and Y-score (partner→FBXW2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	EHMT1 →	+0.348	+0.526	.001	<.001	3	8
GBM	BRD3 →	+0.262	+0.275	<.001	<.001	3	7
OV	ECPAS →	+0.436	+0.654	<.001	<.001	3	7
GBM	FUBP3 →	+0.269	+0.424	<.001	<.001	3	7
LSCC	PRRC2B →	+0.309	+0.408	<.001	<.001	3	7
OV	TBC1D13 →	+0.359	+0.668	.004	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,647 associations by consensus.

FBXW2 vs EHMT1 — COAD

Explore this scatter interactively →