FBXW2

Across TCGA patient cohorts, FBXW2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,599 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FBXW2-associated genes across cancer lineages are FOXM1, CDCA3, and KCND3. Each is linked with FBXW2 in more than 5 cancer types. Because this analysis shows association rather than direction, both FBXW2-to-partner and partner-to-FBXW2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXW2 versus FOXM1 in UCEC, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXW2→partner) and Y-score (partner→FBXW2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXM1 →	-0.915	-0.294	<.001	<.001	3	6
LUAD	CDCA3 →	-0.874	-0.190	<.001	<.001	3	5
BRCA	KCND3 →	+1.219	+0.292	<.001	<.001	3	5
LSCC	ZNF695 →	-0.868	-0.194	.002	.001	3	5
UCEC	ORC6 →	-0.742	-0.232	<.001	<.001	3	5
LUAD	NCAPG →	-0.904	-0.182	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,599 associations by consensus.

FBXW2 vs FOXM1 — UCEC

Explore this scatter interactively →