FBXW2

Across TCGA cell cohorts, FBXW2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,025 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FBXW2-associated GO terms across cancer lineages are RNA export from nucleus, RNA localization, and Nucleic acid transport. Each is linked with FBXW2 in more than 18 cancer types. Because this analysis shows association rather than direction, both FBXW2-to-partner and partner-to-FBXW2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA export from nucleus grouped by FBXW2-low versus FBXW2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXW2→partner) and Y-score (partner→FBXW2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	RNA export from nucleus →	+0.116	+1.144	<.001	<.001	3	19
PANCREAS	RNA localization →	+0.084	+0.954	<.001	<.001	3	19
OESOPHAGUS	Nucleic acid transport →	+0.124	+0.845	.003	.009	3	18
OESOPHAGUS	RNA transport →	+0.124	+0.845	.003	.009	3	18
OESOPHAGUS	mRNA transport →	+0.144	+0.911	.004	.007	3	18
OESOPHAGUS	Nuclear export →	+0.107	+0.916	.005	.006	2	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,025 associations by consensus.

RNA export from nucleus by FBXW2 expression — PANCREAS

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