FBXO7

Across TCGA patient cohorts, FBXO7 mutation is significantly associated with the RNA expression of many other genes, with 1,557 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBXO7-associated genes across cancer lineages are RNU6-1122P, SLC35F6, and EIF3JP1. Each is linked with FBXO7 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO7-to-partner and partner-to-FBXO7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1122P grouped by FBXO7-low versus FBXO7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO7→partner) and Y-score (partner→FBXO7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1122P →	+0.171	+2.037	.001	.009	3	2
UCEC	SLC35F6 →	+0.485	+2.917	<.001	<.001	3	2
UCEC	EIF3JP1 →	+0.123	+1.646	.001	.007	3	2
UCEC	TSPY8 →	+0.004	+4.258	<.001	.003	3	2
UCEC	RN7SL764P →	+0.118	+1.615	.008	.006	3	2
UCEC	RNA5SP422 →	+0.540	+1.671	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,557 associations by consensus.

RNU6-1122P by FBXO7 expression — UCEC

Explore this box plot interactively →