FBXO7

Across TCGA cell cohorts, FBXO7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,759 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible FBXO7-associated GO terms across cancer lineages are Positive regulation of macrophage proliferation, Symbiont-mediated disruption of host cellular anatomical structure, and Symbiont-mediated disruption of host anatomical structure. Each is linked with FBXO7 in more than 11 cancer types. Because this analysis shows association rather than direction, both FBXO7-to-partner and partner-to-FBXO7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of macrophage proliferation grouped by FBXO7-low versus FBXO7-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO7→partner) and Y-score (partner→FBXO7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of macrophage proliferation →	+0.307	+0.685	<.001	<.001	3	12
URINARY_TRACT	Symbiont-mediated disruption of host cellular anatomical structure →	+0.116	+0.506	<.001	<.001	3	12
URINARY_TRACT	Symbiont-mediated disruption of host anatomical structure →	+0.116	+0.506	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.068	+0.548	.001	.007	3	11
OESOPHAGUS	Negative regulation of chromosome condensation →	+0.156	+0.604	.002	.009	2	12
UPPER_AERODIGESTIVE_TRACT	Interleukin-34-mediated signaling pathway →	+0.223	+0.697	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,759 associations by consensus.

Positive regulation of macrophage proliferation by FBXO7 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →